Perimenopause isn't just a reproductive transition — it's a neurological one. Neuroimaging shows measurable declines in brain glucose metabolism starting in perimenopause. Women make up two-thirds of Alzheimer's cases, and hormonal shifts play a key role. This evidence-based guide explores the science, what it means for most women, and proven strategies to protect your cognitive health long-term.

Forgetting words mid-sentence. Walking into rooms and drawing a blank. Feeling like your brain is running on half power. If this sounds familiar, you're not alone — and you're not losing your mind. Perimenopause brain fog affects up to 44% of women in the hormonal transition, and it's driven by estrogen's direct role in brain energy. Here's the science behind it, why it's not dementia, and what actually helps.